Expert hopes ‘fourth-generation’ refractive procedures address limitations of LASIK, surface ablation

NEW ORLEANS — The next generation of corneal refractive surgery is going back to the surface in an effort to resolve surgical limitations of conventional PRK, LASIK and LASEK, according to a keynote lecturer here.

Speaking at the Refractive Subspecialty Day preceding the American Academy of Ophthalmology meeting here, John Marshall, PhD, explained his belief in the fourth generation of corneal refractive surgery.

The three previous generations include early PRK, LASIK, and then LASEK and epi-LASEK, he said. Each of these techniques has its own limitations, he said.

In an effort to chronicle the limitations of conventional surgical techniques, Dr. Marshall said he and his colleagues have begun to study the effect of PRK, LASEK and LASIK at 4 to 6 weeks after surgery on human tissue by using a culture model. He said most research to date has been limited to rabbit or monkey corneas.

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